Events
Hybrid: RCH B102AB, Richards Bldg., 3700 Hamilton Walk (and virtual via Zoom)
Hybrid-Research Ethics and Policy Series (REPS): "What Makes Clinical Research Ethical": A Twenty-Five Year Journey and Look to the Future - Christine Grady, MSN, PhD
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2025-12-09 12:00:00
2025-12-09 13:00:00
America/New_York
Hybrid-Research Ethics and Policy Series (REPS): "What Makes Clinical Research Ethical": A Twenty-Five Year Journey and Look to the Future - Christine Grady, MSN, PhD
"What Makes Clinical Research Ethical": A Twenty-Five Year Journey and Look to the Future
Christine Grady, MSN, PhD
Former Chair, Department of Bioethics,
NIH Clinical Center
Recognizing some uncertainty about the ethics of clinical research and differences in interpretation and implementation of existing guidance, 25 years ago we developed a framework to help investigators, reviewers, and interested others design, implement, and evaluate ethical clinical research. Our framework, consisting initially of 7 and later 8 principles, resonated with many around the globe.
Since then, the framework has been used, debated, and cited in academic publications, national guidelines, presentations, and discussions across a wide spectrum of clinical research. In this presentation, Dr. Grady will discuss the origins of the framework, its contents and elements, how it has been used, some challenges and where more work could be useful.
Dr. Grady has published widely in the biomedical and bioethics literature and authored or edited several books, including The Oxford Textbook of Clinical Research Ethics. Her work is known internationally, and she has lectured widely on ethical issues in clinical research and clinical care, HIV disease, and nursing.
Registration Required. Lunch provided.
Streaming available via Zoom.
Hybrid: RCH B102AB, Richards Bldg., 3700 Hamilton Walk (and virtual via Zoom)
Penn Medical Ethics
1104 Blockley Hall (Note: Virtual attendees can join by accessing this link: https://upenn.zoom.us/j/95740259034.)
Health Policy Research Seminar: Lauren Nicholas PhD, MPP, Professor of Medicine-Geriatrics, University of Colorado Denver
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2025-12-11 10:00:00
2025-12-11 11:00:00
America/New_York
Health Policy Research Seminar: Lauren Nicholas PhD, MPP, Professor of Medicine-Geriatrics, University of Colorado Denver
Topic: "Reliance on Informal Care in Medicare Advantage versus Traditional Medicare."
About the Talk: Recent studies have found lower use of post-acute care among Medicare Advantage enrollees versus Traditional Medicare. In this paper, we test whether informal caregiving accounts for this difference and estimate potential social costs or savings.
About the Speaker: Lauren Hersch Nicholas is a health economist and professor in the division of geriatric medicine. Her research focuses on the role of public policy in improving health and healthcare quality for the elderly. Her current research combines survey, administrative, and clinical data to study the interaction between healthcare utilization and economic outcomes. Dr. Nicholas's work uses clinical and econometric approaches to answer questions in medical and health economics, particularly for dementia, surgery and end-of-life care. She is a leading expert on the financial symptoms and consequences of dementia, work that has been featured in the New York Times, the Wall Street Journal, the Washington Post, and other major media outlets.
1104 Blockley Hall (Note: Virtual attendees can join by accessing this link: https://upenn.zoom.us/j/95740259034.)
Penn Medical Ethics
1104 Blockley Hall (Note: Virtual attendees can join by accessing this link: https://upenn.zoom.us/j/95740259034.)
Health Policy Research Seminar: LJ Ristovskam, PhD, Assistant Professor of Public Affairs, University of Texas-Austin
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2026-01-08 12:00:00
2026-01-08 13:00:00
America/New_York
Health Policy Research Seminar: LJ Ristovskam, PhD, Assistant Professor of Public Affairs, University of Texas-Austin
1104 Blockley Hall (Note: Virtual attendees can join by accessing this link: https://upenn.zoom.us/j/95740259034.)
Penn Medical Ethics
Hybrid: RCH B102AB, Richards Bldg., 3700 Hamilton Walk (and virtual via Zoom)
Research Ethics & Policy Series (REPS): "Research Issues Arising in Alzheimer’s Disease Related Dementias" - Jason Karlawish, MD
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2026-01-13 12:00:00
2026-01-13 13:00:00
America/New_York
Research Ethics & Policy Series (REPS): "Research Issues Arising in Alzheimer’s Disease Related Dementias" - Jason Karlawish, MD
Research Issues Arising in Alzheimer’s Disease Related Dementias
Jason Karlawish, MD
Professor of Medicine, Medical Ethics & Health Policy, and Neurology
Co-Director, Penn Memory Center
University of Pennsylvania
Dr. Jason Karlawish is a professor of medicine, medical ethics and health policy, and neurology at the University of Pennsylvania Perelman School of Medicine. He is board-certified in geriatric medicine. He was educated at Northwestern University, the Johns Hopkins Medical Institutions, and the University of Chicago.
Dr. Karlawish is a Senior Fellow of the Leonard Davis Institute of Health Economics, Senior Fellow of the Penn Center for Public Health Initiatives, fellow of the University of Pennsylvania’s Institute on Aging, director of the Penn Program on Precision Medicine for the Brain (P3MB), Co-Associate Director of the Alzheimer’s Disease Research Center, and co-director of the Penn Memory Center. He is also director of the Alzheimer’s Disease Research Center’s Outreach, Recruitment and Education Core and the center’s Research Education Component.
His research focuses on aging, neuroethics, and policy. He has investigated issues in dementia drug development, informed consent, quality of life, paradoxical lucidity and theory of mind in dementia, research and treatment decision-making, and voting by persons living with dementia.
More detail to follow.
Registration required; Lunch provided.
Streaming available via Zoom.
Hybrid: RCH B102AB, Richards Bldg., 3700 Hamilton Walk (and virtual via Zoom)
Penn Medical Ethics
Virtual, via Zoom
Penn Bioethics Seminar (PBS): "Organ Diversion or Match Run Deviation? Ethical Considerations in Allocation Out of Sequence" - Andrew M. Courtwright, MD, PhD
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2026-01-27 12:00:00
2026-01-27 13:00:00
America/New_York
Penn Bioethics Seminar (PBS): "Organ Diversion or Match Run Deviation? Ethical Considerations in Allocation Out of Sequence" - Andrew M. Courtwright, MD, PhD
Organ Diversion or Match Run Deviation? Ethical Considerations in Allocation Out of Sequence
Andrew M. Courtwright, MD, PhD
Clinician, Division of Pulmonary Medicine
Adjunct Professor, University of Utah Department of Philosophy
University of Utah Health
The rise of Allocation Out of Sequence (AOOS) in organ transplantation in the United States has raised significant ethical concerns. By the end of 2024, 20% of kidneys were transplanted out of the standard match sequence, drawing regulatory scrutiny. Critics argue that AOOS amounts to organ diversion: it fails to prevent organ nonuse, does not address underlying inefficiencies in organ allocation, lacks transparency, and worsens transplant-related disparities.
In this talk, Dr. Courtwright discusses the factors contributing to the expansion of AOOS and evaluates the normative arguments for and against its use. Drawing on a constructivist framework, he argues that AOOS violates the expectation that allocation policies be grounded in collective agreement. Dr. Courtwright identifies considerations that should inform Organ Procurement and Transplantation Network policy revisions, emphasizing the need for shared norms to ensure procedural legitimacy.
Virtual, via Zoom
Penn Medical Ethics
To be added to MEHP's events listserv, please contact lisa.bailey@pennmedicine.upenn.edu.