Penn Bioethics Seminar Series (PBS): Isabel Gabel, PhD

Ethics and the History of Gene Regulation: Findings from the Jacques Monod Archives at the Institut Pasteur in Paris

Isabel Gabel, PhD, Fellow in Ethical, Legal, and Social Implications of Genetics and Genomics, Medical Ethics and Health Policy, PSOM 

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Abstract: Drawing on archival sources from the 1960s, this talk examines how early research on gene regulation became part of a broader cultural conversation about the role of science in a liberal society. Using materials from the Institut Pasteur in Paris, I show how in the wake of their Nobel Prize for their work on the lac operon, François Jacob and Jacques Monod used their roles as trusted public figures to advocate for vision of science that could accommodate both the randomness of life’s emergence and the importance of objective knowledge.  I argue that this moment in the history of genetics research was a turning point in the broader intellectual history of bioethics.

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