Hybrid-Research Ethics and Policy Series (REPS): "What Makes Clinical Research Ethical": A Twenty-Five Year Journey and Look to the Future - Christine Grady, MSN, PhD

12:00pm - 1:00pm • Hybrid: RCH B102AB, Richards Bldg., 3700 Hamilton Walk (and virtual via Zoom)

2025-12-09 12:00:00 2025-12-09 13:00:00 America/New_York Hybrid-Research Ethics and Policy Series (REPS): "What Makes Clinical Research Ethical": A Twenty-Five Year Journey and Look to the Future - Christine Grady, MSN, PhD "What Makes Clinical Research Ethical": A Twenty-Five Year Journey and Look to the Future Christine Grady, MSN, PhD Former Chair, Department of Bioethics, NIH Clinical Center Recognizing some uncertainty about the ethics of clinical research and differences in interpretation and implementation of existing guidance, 25 years ago we developed a framework to help investigators, reviewers, and interested others design, implement, and evaluate ethical clinical research. Our framework, consisting initially of 7 and later 8 principles, resonated with many around the globe. Since then, the framework has been used, debated, and cited in academic publications, national guidelines, presentations, and discussions across a wide spectrum of clinical research. In this presentation, Dr. Grady will discuss the origins of the framework, its contents and elements, how it has been used, some challenges and where more work could be useful. Dr. Grady has published widely in the biomedical and bioethics literature and authored or edited several books, including The Oxford Textbook of Clinical Research Ethics. Her work is known internationally, and she has lectured widely on ethical issues in clinical research and clinical care, HIV disease, and nursing. Registration Required. Lunch provided. Streaming available via Zoom. Hybrid: RCH B102AB, Richards Bldg., 3700 Hamilton Walk (and virtual via Zoom) Penn Medical Ethics

Recognizing some uncertainty about the ethics of clinical research and differences in interpretation and implementation of existing guidance, 25 years ago we developed a framework to help investigators, reviewers, and interested others design, implement, and evaluate ethical clinical research. Our framework, consisting initially of 7 and later 8 principles, resonated with many around the globe.

Since then, the framework has been used, debated, and cited in academic publications, national guidelines, presentations, and discussions across a wide spectrum of clinical research. In this presentation, Dr. Grady will discuss the origins of the framework, its contents and elements, how it has been used, some challenges and where more work could be useful.

Dr. Grady has published widely in the biomedical and bioethics literature and authored or edited several books, including The Oxford Textbook of Clinical Research Ethics. Her work is known internationally, and she has lectured widely on ethical issues in clinical research and clinical care, HIV disease, and nursing.