Angela R. Bradbury

Angela R. Bradbury, MD

angela.bradbury@uphs.upenn.edu
  • Titles:
  • Associate Professor of Medicine
  • Associate Professor of Medical Ethics and Health Policy
  • Education:
  • University of Chicago (Clinical Medical Ethics)
  • University of Chicago (Medical Oncology)
  • University of Chicago (Internal Medicine)
  • Medical University of South Carolina, MD
  • The University of Virginia, BA, Biology

The volume of genomic testing is expected to increase given the large federal and commercial investment in genomic technologies designed to enhance personalized medicine. Translational research that evaluates the implementation, dissemination and “real world” outcomes of existing and new genomic applications is needed to guide the rational clinical integration of genomic advances to ultimately reduce the burden of cancer and improve human health. As a medical oncologist with specialized training in clinical cancer genetics, cancer prevention and medical ethics, I have been developing and leading translational genetic research focused on the ethics and clinical implementation of genetic medicine to promote the health of individuals and families since 2003. This work involves research and academic activities focused on: a) the delivery of genetic services, b) the implications of genetic medicine for children and adolescents and c) Ethical, Legal and Social Issues in genetic medicine. These translational and multidisciplinary studies (further described below) have been supported by the National Institutes of Health, American Cancer Society, Greenwall Foundation Program in Bioethics, American Society of Clinical Oncology and Pennsylvania Department of Health. We expect these studies, and subsequent studies within this research program to increase our understanding of how to incorporate genomic testing into the care of patients and families in a way that benefits the health and minimizes the risks for patients across the lifespan. 

Selected Publications
2017 Journal of oncology practice Jones RD, Sabolch AN, Aakhus E, Spence RA, Bradbury AR, Jagsi R
Patient Perspectives on the Ethical Implementation of a Rapid Learning System for Oncology Care.
2016 Journal of clinical oncology : official journal of the American Society of Clinical Oncology Bradbury AR, Patrick-Miller L, Schwartz LA, Egleston BL, Henry-Moss D, Domchek SM, Daly MB, Tuchman L, Moore C, Rauch PK, Shorter R, Karpink K, Sands CB
Psychosocial Adjustment and Perceived Risk Among Adolescent Girls From Families With BRCA1/2 or Breast Cancer History.
2016 Pediatrics Terry MB, Goldberg M, Schechter S, Houghton LC, White ML, O'Toole K, Chung WK, Daly MB, Keegan TH, Andrulis IL, Bradbury AR, Schwartz L, Knight JA, John EM, Buys SS
Comparison of Clinical, Maternal, and Self Pubertal Assessments: Implications for Health Studies.
2016 American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Meeting Kesserwan C, Friedman Ross L, Bradbury AR, Nichols KE
The Advantages and Challenges of Testing Children for Heritable Predisposition to Cancer.
2016 Epidemiology (Cambridge, Mass.) John EM, Terry MB, Keegan TH, Bradbury AR, Knight JA, Chung WK, Frost CJ, Lilge L, Patrick-Miller L, Schwartz LA, Whittemore AS, Buys SS, Daly MB, Andrulis IL
The LEGACY Girls Study: Growth and Development in the Context of Breast Cancer Family History.
2016 Journal of clinical oncology : official journal of the American Society of Clinical Oncology Henderson TO, Moskowitz CS, Chou JF, Bradbury AR, Neglia JP, Dang CT, Onel K, Novetsky Friedman D, Bhatia S, Strong LC, Stovall M, Kenney LB, Barnea D, Lorenzi E, Hammond S, Leisenring WM, Robison LL, Armstrong GT, Diller LR, Oeffinger KC
Breast Cancer Risk in Childhood Cancer Survivors Without a History of Chest Radiotherapy: A Report From the Childhood Cancer Survivor Study.

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