Penn Bioethics Seminar Series (PBS): Andrew Gellert, PhD

Social Determinants of Health, ACTIVE Training, and Diagnosed Dementia

Andrew Gellert, PhD, Postdoctoral researcher, Medical Ethics and Health Policy, PSOM 

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Description: The Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) trial randomly assigned participants over the age of 65 without a diagnosis of dementia to one of three different cognitive training interventions or to a control group. Participants assigned to the intervention groups have demonstrated cognitive gains as measured by testing and reduced rates of diagnosed Alzheimer’s and related dementia. However, prior work has not examined the extent to which training gains from ACTIVE depend on the social determinants of health that affect the study’s participants, nor how SDoH factors may influence ADRD diagnosis rates. The five domains of social determinants of health are economic stability, education, social and community context, health and health care, and neighborhood and built environment. We explore whether participants’ differences across these five domains yield differential outcomes using ACTIVE survey data, supplemental neighborhood-level Census data, and Medicare claims data.

See speaker's bio here.

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